Beta Amyloid Polyclonal Antibody

• Background:

  This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy) . Multiple transcript variants encoding several different isoforms have been found for this gene.

• Description:

  This is a beta Amyloid Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  A4 amyloid protein, A4, AAA, ABETA, ABPP, AD1, AICD-50, AICD-57, AICD-59, AID (50), AID (57), AID (59), Alzheimer disease amyloid protein, Amyloid beta (A4) precursor protein, Amyloid beta A4 protein, Amyloid beta protein, Amyloid intracellular domain 50, Amyloid intracellul

• Swiss Prot:

  P05067

• Accession Number:

  NP_000475

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide of human APP

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.7 mg/mL

• Dilution:

  WB 1:1000-1:5000, IHC 1:50-1:200

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  87 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG