IDH2 Polyclonal Antibody

CAT: 0866-RD78174A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD78174A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the electron acceptor and the other NADP (+) . Five isocitrate dehydrogenases have been reported: three NAD (+) -dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP (+) -dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP (+) -dependent isozyme is a homodimer. The protein encoded by this gene is the NADP (+) -dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. Alternative splicing results in multiple transcript variants.
Description
This is a IDH2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
D2HGA2, ICD-M, IDH, IDH2, IDHM, IDHP, IDP, IDPM, Isocitrate dehydrogenase [NADP], mitochondrial, Isocitrate dehydrogenase 2 (NADP+), mitochondrial, mNADP-IDH, NADP (+) -specific ICDH, Oxalosuccinate decarboxylase
Swiss Prot
P48735
Accession Number
BC009244
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human IDH2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
51 kDa
Host or Source
Rabbit
Isotype
IgG

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