DCTN4 Polyclonal Antibody

• Background :

  Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.

• Description :

  This is a DCTN4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  DCTN 4, Dctn4, DCTN4, Dynactin 4 (p62), Dynactin 4, Dynactin p62 subunit, Dynactin subunit 4, Dynactin subunit p62, Dynactin4, p62

• Swiss Prot :

  Q9UJW0

• Accession Number :

  BC026323

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein of human DCTN4

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.6 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG