DCTN3 Polyclonal Antibody

• Background :

  This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

• Description :

  This is a DCTN3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  DCNT22, DCTN 22, DCTN22, Dctn3, DCTN3, dynactin 3 (p22), dynactin 3, dynactin 3 isoform 1, Dynactin complex subunit 22 kDa subunit, dynactin light chain, Dynactin subunit 3, p22

• Swiss Prot :

  O75935

• Accession Number :

  BC000319

• Reactivity :

  Human

• Immunogen :

  Recombinant protein of human DCTN3

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.6 mg/mL

• Dilution :

  IHC 1:100-1:300

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG