STAT5A Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X (L), which suggests the antiapoptotic function of this gene in cells.

• Description:

  This is a STAT5A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Mammary gland factor, MGF, Signal transducer and activator of transcription 5A, STA5A, STAT 5, STAT 5A, STAT5, STAT5A

• Swiss Prot:

  P42229

• Accession Number:

  BC027036

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human STAT5A

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.4 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  91 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG