STAT5A Polyclonal Antibody

CAT: 0866-RD77260A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD77260A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X (L), which suggests the antiapoptotic function of this gene in cells.
Description
This is a STAT5A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Mammary gland factor, MGF, Signal transducer and activator of transcription 5A, STA5A, STAT 5, STAT 5A, STAT5, STAT5A
Swiss Prot
P42229
Accession Number
BC027036
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human STAT5A
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.4 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
91 kDa
Host or Source
Rabbit
Isotype
IgG

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