Products for Research Use Only

PTPN13 Polyclonal Antibody

CAT: 0866-RD76833A-01Size: 20 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0866-RD76833A-01Size:20 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Description
This is a PTPN13 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
APO1/CD95 (Fas) associated phosphatase, DKFZp686J1497, FAP 1, FAP1, Fas associated phosphatase 1, Fas associated protein tyrosine phosphatase 1, HGNC:9646, hPTPE1, Phosphatase rip, PNP 1, PNP1, Protein tyrosine phosphatase 1 Fas associated, protein tyrosine phosphata
Swiss Prot
Q12923
Accession Number
NP_542414
Reactivity
Human
Immunogen
Synthetic peptide of human PTPN13
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.5 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG