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PTPN18 Polyclonal Antibody

CAT: 0866-RD267993A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD267993A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, the mitotic cycle, and oncogenic transformation. This PTP contains a PEST motif, which often serves as a protein-protein interaction domain, and may be related to protein intracellular half-live. This protein can differentially dephosphorylate autophosphorylated tyrosine kinases that are overexpressed in tumor tissues, and it appears to regulate HER2, a member of the epidermal growth factor receptor family of receptor tyrosine kinases. Two transcript variants encoding different isoforms have been found for this gene.
Description
This is a PTPN18 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PTPN18, BDP1, PTP-HSCF
Gene ID
26469
Swiss Prot
Q99952
Reactivity
Human
Immunogen
Recombinant fusion protein of human PTPN18 (NP_001135842.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
38 kDa/50 kDa
Observed Molecular Weight
60 kDa
Host or Source
Rabbit
Isotype
IgG

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