CD54 Polyclonal Antibody

• Background :

  This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) . During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

• Description :

  This is a CD54 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Antigen identified by monoclonal BB2, BB 2, BB2, CD 54, CD_antigen=CD54, CD54, Cell surface glycoprotein P3.58, Human rhinovirus receptor, ICAM 1, ICAM-1, ICAM1, ICAM1, intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, Intercellular adhesion molecule

• Swiss Prot :

  P05362

• Accession Number :

  NP_000192

• Reactivity :

  Human

• Immunogen :

  Synthetic peptide of human ICAM1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.3 mg/mL

• Dilution :

  WB 1:500-1:2000, IHC 1:25-1:100

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  58 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG