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ABCA4 Polyclonal Antibody

CAT: 0866-RD76607A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD76607A-01Size:20 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.
Description
This is a ABCA4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ABC 10, ABC A4, ABC transporter, retinal-specific, ABC10, ABCA 4, abcA4, ABCA4, ABCR, ARMD 2, ARMD2, ATP binding cassette 10, ATP binding cassette sub family A member 4, ATP binding cassette sub family A member4, ATP binding cassette transporter, ATP binding cassette tr
Swiss Prot
P78363
Accession Number
NP_000341
Reactivity
Human
Immunogen
Synthetic peptide of human ABCA4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.2 mg/mL
Dilution
IHC 1:25-1:100
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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