ABCA1 Polyclonal Antibody

• Background:

  The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

• Description:

  This is a ABCA1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD

• Gene ID:

  19

• Swiss Prot:

  O95477

• Reactivity:

  Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human ABCA1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  IF 1:50-1:200

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  294kDa/297kDa/301kDa

• Observed Molecular Weight:

  301kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG