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Factor XIIIa Polyclonal Antibody

CAT: 0866-RD76588A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD76588A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Description
This is a Factor XIIIa Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
BA525O21.1 (coagulation factor XIII, A1 polypeptide), Coagulation factor XIII A chain, Coagulation factor XIII A1 polypeptide, Coagulation factor XIII A1 subunit, Coagulation factor XIII, A polypeptide, Coagulation factor XIIIa, F13A, F13A, F13a1, Factor XIIIA, Fibri
Swiss Prot
P00488
Accession Number
NP_000120
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human F13A1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.1 mg/mL
Dilution
IHC 1:100-1:300
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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