STAT6 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

• Description :

  This is a STAT6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  12S1644, D12S1644, IL 4 STAT, IL-4 Stat, IL4 STAT, Interleukin 4 Induced, Interleukin 4 Induced Transcription Factor IL4 STAT, Signal transducer and activator of transcription 6, Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced, Signal Tran

• Swiss Prot :

  P42226

• Accession Number :

  BC075852

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant protein of human STAT6

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.2 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  94 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG