Products for Research Use Only

ALOX5 Polyclonal Antibody

CAT: 0866-RD75005A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD75005A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5 (S) -hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5 (S) -trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4) . Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
This is a ALOX5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
5 LO,5 LOX,5-lipoxygenase,5-LO,5-LOX,5LOX,5LPG, ALOX 5, Alox5, Arachidonate 5 lipoxygenase, Arachidonate 5-lipoxygenase, arachidonic 5-lipoxygenase alpha-10 isoform, arachidonic 5-lipoxygenase delta-10-13 isoform, arachidonic 5-lipoxygenase delta-13 isoform, arac
Swiss Prot
P09917
Accession Number
BC130332
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human ALOX5
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
0.7 mg/mL
Dilution
IHC 1:50-1:150
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG