CD284 Polyclonal Antibody

• Background:

  TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS) . TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

• Description:

  This is a CD284 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ARMD10, CD284, CD284 antigen, Homolog of Drosophila toll, hToll, TLR 4, TLR4, TLR4, TOLL, Toll like receptor 4, Toll-like receptor 4

• Swiss Prot:

  O00206, Q9QUK6, Q9QX05

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  KLH conjugated Synthetic peptide corresponding to Mouse TLR4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.9 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1::500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  95 kDa

• Observed Molecular Weight:

  95 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG