CD163 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

• Description :

  This is a CD163 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  C163A, CD 163, CD163, CD163 antigen, CD163 molecule, Hemoglobin scavenger receptor, M130, M130 antigen precursor, Macrophage associated antigen, MM130, OTTHUMP00000238617, OTTHUMP00000238618, OTTHUMP00000238619, OTTHUMP00000238620, SCARI1, Scavenger receptor cysteine ri

• Swiss Prot :

  Q86VB7, Q2VLH6

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein corresponding to Mouse CD163

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  360 μg/mL

• Dilution :

  WB 1:1000-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  125 kDa

• Observed Molecular Weight :

  145 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG