CD156c Polyclonal Antibody

• Background:

  Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP) .

• Description:

  This is a CD156c Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  A disintegrin and metalloprotease domain 10, A disintegrin and metalloproteinase domain 10, AD 10, AD10, AD18, ADA10, ADAM 10, ADAM metallopeptidase domain 10, ADAM10, CD 156c, CD156c, CD156c antigen, CDw156, disintegrin and metalloproteinase domain containing protein

• Swiss Prot:

  O14672, O35598, Q10743

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  KLH conjugated Synthetic peptide corresponding to Mouse ADAM10

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  210 μg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  84 kDa

• Observed Molecular Weight:

  95 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG