ITGAV Polyclonal Antibody

• Background :

  The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.

• Description :

  This is a ITGAV Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  Antigen identified by monoclonal L230, CD 51, CD51, DKFZp686A08142, Integrin alpha five, integrin alpha V beta 3, Integrin alpha-5, integrin alpha-V, Integrin alpha-V light chain, integrin alphaVbeta3, integrin, alpha V (vitronectin receptor, alpha polypeptide, antige

• Swiss Prot :

  P06756, P43406

• Reactivity :

  Human, Mouse

• Immunogen :

  KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.76 mg/mL

• Dilution :

  WB 1:500-1:1000

• Buffer :

  PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  116 kDa

• Observed Molecular Weight :

  130 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG