ITGA6 Polyclonal Antibody

• Background:

  The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.

• Description:

  This is a ITGA6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CD49f, ITGA6B, VLA-6, Integrin alpha 6, ITGA6

• Gene ID:

  3655

• Swiss Prot:

  P23229

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human ITGA6

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  86kDa

• Observed Molecular Weight:

  86KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG