CD284 Polyclonal Antibody

• Background :

  TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS) . TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

• Description :

  This is a CD284 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  ARMD10, CD284, CD284 antigen, Homolog of Drosophila toll, hToll, TLR 4, TLR4, TLR4, TOLL, Toll like receptor 4, Toll-like receptor 4

• Swiss Prot :

  O00206, Q9QUK6, Q9QX05

• Reactivity :

  Human, Rat

• Immunogen :

  KLH conjugated Synthetic peptide corresponding to Mouse TLR4

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1.1 mg/mL

• Dilution :

  IHC 1:200-1:800

• Buffer :

  PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG