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SEC31A Polyclonal Antibody

CAT: 0866-RD268016A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD268016A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII) . The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
This is a SEC31A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
SEC31A, ABP125, ABP130, HSPC275, HSPC334, SEC31L1
Gene ID
22872
Swiss Prot
O94979
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human SEC31A (NP_055748.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:1000-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
56 kDa/105-134 kDa
Observed Molecular Weight
165 kDa
Host or Source
Rabbit
Isotype
IgG

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