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Danthron

CAT: 0804-HY-B0923-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0923-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Danthron is a natural product extracted from the traditional Chinese medicine Salvia miltiorrhiza Bunge. Danthron functions in regulating glucose and lipid metabolism by activating AMPK.
CAS Number
117-10-2
Product Name Alternative
Dantron; Chrysazin; 1,8-Dihydroxyanthraquinone
UNSPSC
12352005
Hazard Statement
H315, H319, H335, H351
Target
AMPK; Autophagy; Bacterial; Virus Protease
Type
Natural Products
Related Pathways
Anti-infection; Autophagy; Epigenetics; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Danthron.html
Purity
99.41
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C1C2=C(C=CC=C2O)C(C3=CC=CC(O)=C13)=O
Molecular Formula
C14H8O4
Molecular Weight
240.21
Precautions
H315, H319, H335, H351
References & Citations
[1]Zhou R, et al. Danthron activates AMP-activated protein kinase and regulates lipid and glucose metabolism in vitro. Acta Pharmacol Sin. 2013 Aug;34 (8) :1061-9.|[2]Zhang H, et al. Danthron functions as a retinoic X receptor antagonist by stabilizing tetramers of the receptor. J Biol Chem. 2011 Jan 21;286 (3) :1868-75.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
AMPK

Alternative Products

CatalogName
BUP19608Danthron
AR-A06672-01Danthron-d4 (1,8-Dihydroxyanthraquinone-d4)

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