PRKCG Polyclonal Antibody

CAT: 0866-RD267928A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD267928A-01Size:60 μL
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Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14) . Two transcript variants encoding different isoforms have been found for this gene.
Description
This is a PRKCG Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PRKCG, PKC-gamma, PKCC, PKCG, SCA14
Gene ID
5582
Swiss Prot
P05129
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human PRKCG
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
62 kDa/78 kDa
Observed Molecular Weight
78 kDa
Host or Source
Rabbit
Isotype
IgG

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