PRKCZ Polyclonal Antibody

CAT: 0866-RD266234A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD266234A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
This is a PRKCZ Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PRKCZ, PKC-ZETA, PKC2
Gene ID
5590
Swiss Prot
Q05513
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PRKCZ (NP_002735.3) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
46 kDa/56 kDa/67 kDa
Observed Molecular Weight
78 kDa
Host or Source
Rabbit
Isotype
IgG

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