PDE3A Polyclonal Antibody

• Background:

  This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Description:

  This is a PDE3A Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  HTNB, CGI-PDE, CGI-PDE A, CGI-PDE-A, PDE3A

• Gene ID:

  5139

• Swiss Prot:

  Q14432

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human PDE3A (NP_000912.3) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  IHC 1:50-1:100 IF 1:50-1:100

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG