PIM1 Polyclonal Antibody

CAT: 0866-RD266245A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD266245A-01Size:60 μL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810) .
Description
This is a PIM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PIM, PIM1, PIM1
Gene ID
5292
Swiss Prot
P11309
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PIM1 (NP_002639.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
35 kDa/45 kDa
Observed Molecular Weight
35 kDa
Host or Source
Rabbit
Isotype
IgG

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