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NOTCH3 Polyclonal Antibody

CAT: 0866-RD266095A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD266095A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) .
Description
This is a NOTCH3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NOTCH3, CADASIL, CADASIL1, CASIL, IMF2, LMNS, notch 3
Gene ID
4854
Swiss Prot
Q9UM47
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human NOTCH3 (NP_000426.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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