EP300 Polyclonal Antibody

CAT: 0866-RD265993A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD265993A-01Size:60 μL
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Background
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
Description
This is a EP300 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
EP300, KAT3B, RSTS2, p300
Gene ID
2033
Swiss Prot
Q09472
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human EP300 (NP_001420.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
IHC 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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