PGC1 alpha Polyclonal Antibody

• Background:

  The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs) . It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

• Description:

  This is a PGC1 alpha Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PPARGC1A, LEM6, PGC-1 (alpha), PGC-1alpha, PGC-1v, PGC1, PGC1A, PPARGC1, PPARG coactivator 1 alpha, PGC1 alpha

• Gene ID:

  10891

• Swiss Prot:

  Q9UBK2

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human PGC1 alpha (NP_037393.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000 IF 1:50-1:200

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  14 kDa/30 kDa/31 kDa/33 kDa/77 kDa/89 kDa/91 kDa

• Observed Molecular Weight:

  110 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG