PGC1 alpha Polyclonal Antibody
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PGC1 alpha Polyclonal Antibody
Background :
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs) . It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.Abbreviation :
PGC1 alphaUniProt :
Q9UBK2Host :
RabbitReactivity :
Human; Mouse; RatImmunogen :
A synthetic peptide of human PGC1 alpha (NP_037393.1) .Target :
PPARGC1A; LEM6; PGC-1 (alpha) ; PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1; PPARG coactivator 1 alpha; PGC1 alphaClonality :
PolyclonalConjugation :
UnconjugatedApplications :
WB; IFField of Research :
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; MetabolismPurification :
Affinity purificationConcentration :
1mg/mLDilution :
WB 1:500-1:2000; IF 1:50-1:200Buffer :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.Shipping Conditions :
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.Storage Conditions :
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.Calculated Molecular Weight :
14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDaObserved Molecular Weight :
110kDaCitation 01 :
https://www.sciencedirect.com/science/article/pii/S0024320522009584Citation 02 :
https://onlinelibrary.wiley.com/doi/abs/10.1096/fj.201901510RRCitation 03 :
https://www.sciencedirect.com/science/article/pii/S0024320522003496Isotype :
IgG
