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PGC1 alpha Polyclonal Antibody

CAT: 0763-E-AB-65852-01Size: 60 µLDry Ice: NoHazardous: No
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CAT#:0763-E-AB-65852-01Size:60 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs) . It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Abbreviation
PGC1 alpha
UniProt
Q9UBK2
Host
Rabbit
Reactivity
Human; Mouse; Rat
Immunogen
A synthetic peptide of human PGC1 alpha (NP_037393.1) .
Target
PPARGC1A; LEM6; PGC-1 (alpha) ; PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1; PPARG coactivator 1 alpha; PGC1 alpha
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB; IF
Field of Research
Cancer; Cardiovascular; Epigenetics and Nuclear Signaling; Metabolism
Purification
Affinity purification
Concentration
1mg/mL
Dilution
WB 1:500-1:2000; IF 1:50-1:200
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
14kDa/30kDa/31kDa/33kDa/77kDa/89kDa/91kDa
Observed Molecular Weight
110kDa
Citation 01
https://www.sciencedirect.com/science/article/pii/S0024320522009584
Citation 02
https://onlinelibrary.wiley.com/doi/abs/10.1096/fj.201901510RR
Citation 03
https://www.sciencedirect.com/science/article/pii/S0024320522003496
Isotype
IgG

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