STAT6 Polyclonal Antibody

CAT: 0866-RD265706A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD265706A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
Description
This is a STAT6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
D12S1644, IL-4-STAT, STAT6B, STAT6C, STAT6
Gene ID
6778
Swiss Prot
P42226
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human STAT6 (NP_001171550.1) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
74 kDa/81 kDa/94 kDa
Observed Molecular Weight
110 kDa
Host or Source
Rabbit
Isotype
IgG

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