STAT6 Polyclonal Antibody

• Background :

  The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

• Description :

  This is a STAT6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  D12S1644, IL-4-STAT, STAT6B, STAT6C, STAT6

• Gene ID :

  6778

• Swiss Prot :

  P42226

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human STAT6 (NP_001171550.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  74 kDa/81 kDa/94 kDa

• Observed Molecular Weight :

  110 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG