STAT6 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

• Description:

  This is a STAT6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  D12S1644, IL-4-STAT, STAT6B, STAT6C, STAT6

• Gene ID:

  6778

• Swiss Prot:

  P42226

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human STAT6 (NP_001171550.1) .

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  74 kDa/81 kDa/94 kDa

• Observed Molecular Weight:

  110 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG