Perforin Polyclonal Antibody

• Background :

  The protein encoded by this gene has structural and functional similarities to complement component 9 (C9) . Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.

• Description :

  This is a Perforin Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  PRF1, FLH2, HPLH2, P1, PFN1, PFP, perforin-1, Perforin

• Gene ID :

  5551

• Swiss Prot :

  P14222

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein of human Perforin (NP_001076585.1) .

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  61 kDa

• Observed Molecular Weight :

  70 kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG