PLA2G16 Polyclonal Antibody

CAT: 0866-RD253452A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD253452A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Secretory phopholipase A2 (PLA2) enzymes cleave an acyl ester bond in the sn-2 position of glycerophospholipids. These extracellular proteins have a high disulfide bond content, low molecular mass (14 kDa), and require mM levels of Ca2+ for catalysis. They play a crucial role in the generation of arachidonates and eicosanoids, and have a number of biological actions including immunological responses, inflammation, cellular proliferation, vasoconstriction, and bronchioconstriction. Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphatidylcholines (PC) and phosphatidylethanolamine (PE) . For most substrates, PLA1 activity is much higher than PLA2 activity. Specifically catalyzes the release of fatty acids from phospholipids in adipose tissue (By similarity) . N- and O-acylation activity is hardly detectable. Might decrease protein phosphatase 2A (PP2A) activity.
Description
This is a PLA2G16 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Adipose specific phospholipase A2, Adipose specific PLA2, Adipose-specific phospholipase A2, AdPLA, Ca independent phospholipase A1/2, Group XVI phospholipase A1/A2, Group XVI phospholipase A2, H rev 107 protein homolog, H REV107 1, H-rev 107 protein homolog, HRAS
Swiss Prot
P53816
Accession Number
NP009000
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide of human PLA2G16
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.1 mg/mL
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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