PSCA Polyclonal Antibody

• Background:

  PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.

• Description:

  This is a PSCA Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PRO 232, PRO232, Prostate stem cell antigen

• Swiss Prot:

  O43653

• Accession Number:

  Hs.652235

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human PSCA

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.78 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  13 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG