Products for Research Use Only

GFRA2 Polyclonal Antibody

CAT: 0866-RD253256A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD253256A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI) -linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene.
Description
This is a GFRA2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GDNF family receptor alpha 2, GDNF family receptor alpha-2, GDNF receptor alpha-2, GDNF receptor beta, GDNFR beta, GDNFR-alpha-2, GDNFR-beta, GDNFRB, GFR alpha 2, GFR-alpha-2, GFRA 2, Gfra2, GFRA2, Glial cell line derived neurotrophic factor family receptor alpha2b, Gl
Swiss Prot
O00451
Accession Number
NP001486
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human GFRA2
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.6 mg/mL
Dilution
WB 1:500-1:2000, ELISA 1:1000-1:2000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
52 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG