RITA1 Polyclonal Antibody

• Background:

  Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

• Description:

  This is a RITA1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  C12orf52 , Chromosome 12 open reading frame 52 , RBPJ interacting and tubulin associated 1, RBPJ interacting and tubulin associated protein 1, RBPJ-interacting and tubulin-associated protein, RITA, RITA

• Swiss Prot:

  Q96K30

• Accession Number:

  BC022092

• Reactivity:

  Human

• Immunogen:

  Fusion protein of human RITA1

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.9 mg/mL

• Dilution:

  IHC 1:50-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG