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LFNG Polyclonal Antibody

CAT: 0866-RD253116A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD253116A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150) . Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene.
Description
This is a LFNG Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
3-N-acetylglucosaminyltransferase lunatic fringe, Beta-1, Beta-13-N-acetylglucosaminyltransferase lunatic fringe, lfng, LFNG, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, SCDO3
Swiss Prot
Q8NES3
Accession Number
BC014851
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human LFNG
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.08 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
42 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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