PPM1M Polyclonal Antibody

• Background:

  PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX) . PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42) .

• Description:

  This is a PPM1M Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  FLJ32332, PP2C eta, PP2C-eta, PP2CE, PP2Ceta, PPM1M, PPM1M, protein phosphatase 1M (PP2C domain containing), Protein phosphatase 1M, Protein phosphatase 2C isoform eta

• Swiss Prot:

  Q96MI6

• Accession Number:

  BC009644

• Reactivity:

  Human, Mouse

• Immunogen:

  Fusion protein of human PPM1M

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.78 mg/mL

• Dilution:

  IHC 1:50-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG