SIGLEC6 Polyclonal Antibody

• Background:

  TheSIGLEC6gene to 19q13.3, which is where the CD33 gene is located. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.

• Description:

  This is a SIGLEC6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CD327, CD33 antigen-like 1, CD33L, CD33L1, CD33L2, CDw327, OB-BP1, OBBP1, Obesity-binding protein 1, Sialic acid-binding Ig-like lectin 6, SIGL6, Siglec-6, SIGLEC6

• Swiss Prot:

  O43699

• Accession Number:

  BC035359

• Reactivity:

  Human

• Immunogen:

  Fusion protein of human SIGLEC6

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.78 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  50 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG