CDKL4 Polyclonal Antibody

• Background :

  Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks) . Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.

• Description :

  This is a CDKL4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CDKL4, CDKL4, Cyclin dependent kinase like 4, Cyclin-dependent kinase-like 4, EC 2.7.11.22, OTTHUMP00000164944

• Swiss Prot :

  Q5MAI5

• Accession Number :

  NP001009565

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthetic peptide of human CDKL4

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IHC, ELISA

• Purification Method :

  Antigen affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.8 mg/mL

• Dilution :

  WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

• Buffer :

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  43 kDa

• Observed Molecular Weight :

  Refer to figures

• Host or Source :

  Rabbit

• Isotype :

  IgG