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SPTA1 Polyclonal Antibody

CAT: 0866-RD219527A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD219527A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.
Description
This is a SPTA1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
Alpha I spectrin, EL 2, EL2, Elliptocytosis 2, Elliptocytosis2, Erythrocyte alpha spectrin, erythrocyte, Erythroid alpha spectrin, Erythroid alpha-spectrin, Erythroid spectrin alpha, HPP, HS3, Spectrin alpha chain, Spectrin alpha chain erythrocyte, Spectrin alpha eryth
Swiss Prot
P02549
Accession Number
NP003117
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human SPTA1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.7 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:60-1:450, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
280 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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