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FOXK1 Polyclonal Antibody

CAT: 0866-RD219286A-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0866-RD219286A-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP) . Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.
Description
This is a FOXK1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
A630048H08Rik, AI463295, ENSMUSG00000075577, FHX, Fork head, Forkhead box protein K1, FOXJ2 forkhead factor, FOXK1, FOXK1, Gm10868, MNF, Myocyte nuclear factor
Swiss Prot
P85037
Accession Number
NP001032242
Reactivity
Human, Mouse
Immunogen
Synthetic peptide of human FOXK1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
1.5 mg/mL
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
75 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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