NIPBL Polyclonal Antibody

• Background:

  This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a NIPBL Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CDLS, Colon tumor susceptibility 2, Delangin, DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, FLJ44854, IDN 3, IDN 3 protein, IDN 3 protein isoform A, IDN 3 protein isoform B, IDN 3B, IDN3 B, IDN3 protein, IDN3 protein isoform A, IDN3 protein isoform B, IDN3B, Mis 4

• Swiss Prot:

  Q6KC79

• Accession Number:

  BC033847

• Reactivity:

  Human, Mouse

• Immunogen:

  Fusion protein of human NIPBL

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.9 mg/mL

• Dilution:

  IHC 1:50-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG