GTF2A2 Polyclonal Antibody

• Background:

  Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972) . The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]) .

• Description:

  This is a GTF2A2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  General transcription factor IIA, General transcription factor IIA subunit 2, General transcription factor IIA, 2 (12kD subunit), General transcription factor IIA, 2, 12kDa, gtf2a2, HsT18745, T2AG, TF2A2, TFIIA 12, TFIIA, TFIIA gamma , TFIIA p12 subunit, TFIIA-12, TFI

• Swiss Prot:

  P52657

• Accession Number:

  BC000287

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Fusion protein of human GTF2A2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.54 mg/mL

• Dilution:

  IHC 1:30-1:150, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG