PSMD12 Polyclonal Antibody

CAT: 0866-RD218838A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD218838A-01Size:20 µL
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Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Description
This is a PSMD12 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
26S proteasome non-ATPase regulatory subunit 12,26S proteasome regulatory subunit p55,26S proteasome regulatory subunit RPN5, MGC75406, p55, proteasome (prosome, macropain) 26S subunit, non ATPase12, Proteasome 26S non ATPase subunit 12 isoform 2, PSD12, PSMD12, R
Swiss Prot
O00232
Accession Number
BC019062
Reactivity
Human, Mouse, Rat
Immunogen
Fusion protein of human PSMD12
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.72 mg/mL
Dilution
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
53 kDa
Observed Molecular Weight
Refer to figures
Host or Source
Rabbit
Isotype
IgG

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