PSMD1 Polyclonal Antibody

CAT: 0866-RD266809A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD266809A-01Size:60 μL
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Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. Alternatively spliced transcript variants have been found for this gene.
Description
This is a PSMD1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
PSMD1, P112, Rpn2, S1
Gene ID
5707
Swiss Prot
Q99460
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PSMD1 (NP_002798.2) .
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
102 kDa/105 kDa
Observed Molecular Weight
106 kDa
Host or Source
Rabbit
Isotype
IgG

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