ITGA3 Polyclonal Antibody

• Background:

  ITGA3, also named as MSK18, CD49c, GAPB3 and FRP-2, belongs to the integrin alpha chain family. It is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain (840aa) and light chain (176aa) . This antibody can recognize the heavy chain.

• Description:

  This is a ITGA3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  AA407068, Antigen identified by monoclonal J143, CD49 antigen like family member C, CD49 antigen-like family member C, CD49c, CD49c antigen, FLJ34631, FLJ34704, FRP 2, FRP-2, FRP2, Galactoprotein B3, GAP B3, GAPB3, Integrin alpha 3, Integrin alpha-3 light chain, Integrin

• Swiss Prot:

  P26006

• Accession Number:

  NP002195

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human ITGA3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  1.32 mg/mL

• Dilution:

  IHC 1:40-1:200, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG