COX6C Polyclonal Antibody

• Background:

  Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.

• Description:

  This is a COX6C Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  COX 6C, Cox6c, COX6C, Cytochrome c oxidase polypeptide VIc, Cytochrome c oxidase subunit 6C, cytochrome c oxidase subunit VIc, Cytochrome c oxidase subunit VIc preprotein

• Swiss Prot:

  P09669

• Accession Number:

  NP004365

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human COX6C

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.7 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  9 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG