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L-054522

CAT: 0804-HY-120287Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120287Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-054522 is an agonist for somatostatin receptor subtype 2 with Kd of 0.01 nM. L-054522 inhibits growth hormone release from rat primary pituitary cell (IC50=0.05 nM) and glucagon and insulin release from isolated mouse pancreatic islet cell (IC50=0.05 nM and 12 nM) [1].
CAS Number
214348-67-1
UNSPSC
12352005
Target
Somatostatin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/l-054522.html
Smiles
O=C([C@H](CCCCN)NC([C@@H]([C@@H](C)C1=CNC2=C1C=CC=C2)NC(N3CCC(CC3)N4C5=CC=CC=C5NC4=O)=O)=O)OC(C)(C)C
Molecular Formula
C35H47N7O5
Molecular Weight
645.79
References & Citations
[1]Yang L, et al., Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2. Proc Natl Acad Sci U S A. 1998 Sep 1;95 (18) :10836-41.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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