Anti-PHC3 Antibody (C-Term)

• Background:

  Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

• Description:

  Boster Bio Anti-PHC3 Antibody (C-Term) (Catalog # M08917) . Tested in WB, IHC-P application (s) . This antibody reacts with Human.

• Synonyms:

  Polyhomeotic-like protein 3, Early development regulatory protein 3, Homolog of polyhomeotic 3, hPH3, PHC3, EDR3, PH3

• Gene Name:

  PHC3

• UniProt:

  Q8NDX5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PHC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 819-850 amino acids from human PHC3.

• Clonality:

  Polyclonal

• Applications:

  WB, IHC-P

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

• Molecular Weight:

  106162 Da

• Shipping Conditions:

  Available

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long-term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Subcellular Location:

  Nucleus