IP-10 Mouse Recombinant Protein (CXCL10)

• Description:

  IP-10 Mouse Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 77 amino acids and having a molecular mass of 8701 Dalton. The IP-10 is purified by proprietary chromatographic techniques.

• Synonyms:

  Small inducible cytokine B10; CXCL10; 10 kDa; Gamma-IP10; IP-10; chemokine (C-X-C motif) ligand 10; C7; IFI10; INP10; crg-2; mob-1; SCYB10; gIP-10

• Gene Name:

  CXCL10

• UniProt:

  P17515

• Reactivity:

  Mouse

• Tissue Specificity:

  Expressed in the spleen, thymus, lymph nodes and liver.

• Source:

  Escherichia coli

• Sequence:

  [object Object]

• Purification:

  Greater than 97.0% as determined by (a) Analysis by RP-HPLC and (b) Analysis by SDS-PAGE.

• Bioactivity:

  Determined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 100.0-500.0 ng/ml.

• Form:

  Sterile Filtered White lyophilized (freeze-dried) powder.

• Reconstitution:

  It is recommended to reconstitute the lyophilized IP-10 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

• Function:

  In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.

• Shipping Conditions:

  Available

• Storage Conditions:

  Lyophilized IP-10 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL10 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Please prevent freeze-thaw cycles.

• Other Gene Names:

  C-X-C motif chemokine 10

• Subcellular Location:

  Secreted.